Round zero is included in the price cycle. Ideally if you have in mind a very early upgrade, you could look at culling rookies with the round 4 bye, as they will have had a month's worth of games in their pricing. Someone like Prior would be ideal as he is already starting from an elevated price.
Like I'm not saying this is a particularly optimal strategy but it could be looked at.
(Prior probably has shaky JS and has to make the 22 anyway, just using him as an example)