I'm thinking that the points loss is going to be greater from those players missing the early byes because that loss isn't spread out over the whole season. Teams could be completed earlier, but that's purely down to cash gen.
What is does mean, for me anyway, is that the sideways trading of premos over those early byes is way less risky. For instance, starting Green who has WCE and North matchups in rnds 1 & 2 then flicking him to Walsh in Rnd 3 becomes viable, miss his bye and free up a bit of cash for corrections.