It will always be a hindsight thing, but a lot will come down to how the injuries land over the second part of the year. A lot of teams are rocketing towards full premium but my not have the trades or bench depth to cover injuries over the second half of the year, so there is a world where those with trades in hand can navigate some tricky 1-2 week injuries and come home strong. But if things in the second half aren't too bad, or there ends up being some great final downgrade rookies that hold their spots and score well, then I think those who were conservative will have given up too much ground to chase down.
FWIW going into this round I've used 15 trades and had 15 keepers (+3 from starting team) plus Powell. I'm leaning towards using 2 this week to upgrade Powell, but may use Darcy instead. So I've potentially got 16-17 keepers from 17 trades. Feels well ahead of where I've been in previous years.